TRICHY . BIOMEDICAL V SEM SYLLABUS

ANNA UNIVERSITY TIRUCHIRAPPALLI Tiruchirappalli - 620 024
Regulations 2007 Curriculum
B.E. BIOMEDICAL ENGINEERING
SEMESTER V
S.No. Subject Code Subject L T P Max. Marks
Theory
1 Microprocessors and Microcontrollers 3 1 0 100
2 Biomedical Instrumentation 3 0 0 100
3 Digital Signal Processing 3 1 0 100
4 Bio Control systems 3 1 0 100
5 Biomaterials and Artificial organs 3 0 0 100
6 Environmental Science and Engineering 3 0 0 100
Practical
7 Microprocessors and Microcontrollers Laboratory 0 0 3 100
8 Biomedical Instrumentation Laboratory 0 0 3 100
9 Digital Signal Processing Laboratory 0 0 3 100
ANNA UNIVERSITY TIRUCHIRAPPALLI
Tiruchirappalli - 620 024
Regulations 2007
Syllabus
B.E. BIOMEDICAL ENGINEERING
SEMESTER V
MICROPROCESSORS AND MICROCONTROLLERS
L T P
3 10
UNIT I 8085 MICROPROCESSOR 9
8085 Architecture - Instruction Set - Addressing Modes - Timing Diagrams - Assembly Language Programming - Counters - Time Delays - Interrupts - Memory Interfacing -Interfacing , I/O devices.
UNIT II PERIPHERALS INTERFACING OF 8085 9
Interfacing Serial I/O (8251) - Parallel I/O (8255) - Keyboard and Display Controller (8279) - ADC/DAC Interfacing - Inter Integrated Circuits Interfacing (I2C Standard) -Bus: RS232C - RS485 - GPIB
UNIT III 8086 MICROPROCESSOR 9
8086 Internal Architecture - 8086 Addressing modes - Instruction Set - 8086 Assembly Language Programming - Interrupts.
UNIT IV 8051 MICROCONTROLLER 9
8051 Micro Controller Hardware - I/O Pins, Ports and Circuits - External Memory -Counters and Timers - Serial Data I/O - Interrupts-Interfacing to External Memory and
8255.
UNIT V 8051 PROGRAMMING AND APPLICATIONS 9
8051 Instruction Set - Addressing Modes - Assembly Language Programming - I/O Port Programming - Timer and Counter Programming - Serial Communication - Interrupt Programming - 8051 Interfacing - LCD - ADC - Sensors - Stepper Motors - Keyboard
and DAC.
L: 45 T: 15 TOTAL: 60
TEXT BOOKS
1. Ramesh S Gaonkar, "Microprocessor Architecture, Programming and application with 8085", Fourth Edition, PHI, New Delhi, 2000.
2. John Uffenbeck, "The 80x86 Families, Design, Programming and Interfacing", Third Edition, Pearson Education, 2002.
3. Mohammed Ali Mazidi and Janice Gillispie Mazidi, "The 8051 Microcontroller and Embedded Systems", Pearson Education Asia, New Delhi, 2003.
REFERENCES
1. A.K. Ray and K.M.Burchandi, "Intel Microprocessors Architecture Programming and Interfacing", TMH International Edition, 2000
2. Kenneth J Ayala, "The 8051 Microcontroller Architecture Programming and Application", Second Edition, Penram International Publishers (India), New Delhi,
1996.
3. M. Rafiquzhman, "Microprocessors Theory and Applications: Intel and Motorola", PHI Pvt. Ltd., New Delhi, 2003.
BIOMEDICAL INSTRUMENTATION
LT P 3 0 0
UNIT I BIO-POTENTIAL ELECTRODES 9
Electrode Electrolyte Interface - Half-Cell Potential - Polarisation and Non-Polarisable Electrode - Calomel Electrode - Needle and Wire Electrode - Microelectrode - Metal Micropipette.
UNIT II RECORDING SYSTEM 9
Low-Noise Preamplifier - Main Amplifier and Driver Amplifier - Inkjet Recorder-Thermal Array Recorder - Photographic Recorder - Magnetic Tape Recorder - X-Y Recorder - Medical Oscilloscope.
UNIT III BIO-CHEMICAL MEASUREMENT 9
Ph - pO2 - pCO2 - pHCO3 - Electrophoresis - Calorimeter - Spectro Photometer - Flame Photometer - Auto Analyser.
UNIT IV NON-ELECTRICAL PARAMETER MEASUREMENTS 9
Respiration - Heart Rate - Temperature - Pulse Blood Pressure - Cardiac Output - O2 -CO2 Measurements.
UNIT V BLOOD FLOW AND BLOOD CELL COUNTING 9
Electromagnetic and Ultrasonic Blood Flowmeter - Indicator Dilution Method -Thermodilution Method - Manual and Automatic Counting Of RBC - WBC and Platelets.
Total : 45
TEXT BOOK
1. Leslie Cromwell, "Biomedical Instrumentation and Measurement", Prentice Hall of India, New Delhi, 1997.
REFERENCES
1. John G. Webster, "Medical Instrumentation Application and Design", John Wiley and Sons, New York, 1998.
2. Khandpur R. S, "Handbook of Biomedical Instrumentation", Tata McGraw-Hill,
New Delhi, 1997.
3. Joseph J. carr and John M. Brown, "Introduction to Biomedical Equipment Technology", John Wiley and Sons, New York, 1997.
DIGITAL SIGNAL PROCESSING
LTP 3 10
UNIT I FAST FOURIER TRANSFORM 9
Introduction to DFT - Efficient Computation of DFT Properties of DFT - FFT Algorithms - Radix-2 FFT Algorithms - Decimation in Time - Decimation in Frequency Algorithms -Use Of FFT Algorithms in Linear Filtering and Correlation.
UNIT II DIGITAL FILTER DESIGN 9
Amplitude and Phase Responses of FIR Filters - Linear Phase Filters - Windowing Techniques for Design of Linear Phase FIR Filters - Rectangular, Hamming, Kaiser Window - Frequency Sampling Techniques - IIR Filters - Magnitude Response - Phase Response - Group Delay - Design of Low Pass Butterworth Filters (Low Pass) - Bilinear Transformation - Prewarping - Impulse Invariant Transformation.
UNIT III FINITE WORD LENGTH EFFECTS 9
Quantization Noise - Derivation for Quantization Noise Power - Fixed Point and Binary Floating Point Number Representation - Comparison - Over Flow Error - Truncation Error - Co-Efficient Quantization Error - Limit Cycle Oscillation - Signal Scaling -Analytical Model of Sample and Hold Operations.
UNIT IV POWER SPECTRUM ESTIMATION 9
Computation of Energy Density Spectrum - Auto Correlation and Power Spectrum of Random Signals. Periodogram - Use of DFT in Power Spectrum Estimation - Non Parametric Methods for Power Spectral Estimation: Bartlett and Welch Methods -Blackman and Tukey Method.
UNIT V DIGITAL SIGNAL PROCESSORS 9
Introduction to DSP Architecture -Harvard Architecture - Dedicated MAC Unit - Multiple Alus, Advanced Addressing Modes - Pipelining - Overview of Instruction Set of TMS320C5X and C54X.
L:45 T:15 TOTAL: 60
TEXT BOOKS
1. John G Proakis, Dimtris G Manolakis, "Digital Signal Processing Principles, Algorithms and Application", PHI, Third Edition, 2000.
2. B. Venkataramani & M. Bhaskar, "Digital Signal Processor Architecture, Programming and Application", TMH, 2002.
REFERENCES
1. Alan V Oppenheim, Ronald W Schafer, John R Back, "Discrete Time Signal Processing", Second Edition , PHI, 2000.
2. Johny R.Johnson, "Introduction to Digital Signal Processing", PHI, 1984.
3. S. K. Mitra, "Digital Signal Processing- A Computer based approach", TMH, New
Delhi, 1998.
BIO CONTROL SYSTEMS
LTP 3 10
UNIT I CONTROL SYSTEM MODELLING 9
System Concept - Differential Equations - Transfer Functions - Modelling of Electrical Systems - Translational and Rotational Mechanical Systems - Electro-Mechanical Systems - Physiological Systems - Block Diagram Modelling - Signal Flow Graphs.
UNIT II TIME RESPONSE ANALYSIS 9
Time Domain Specifications - Step and Impulse Response Analysis of First Order and Second Order Systems - Steady State Errors - Stability - Routh-Hurwitz Criteria - Root Locus Techniques - Construction of Root Locus - Stability - Dominant Poles -Applications of Root Locus Diagram.
UNIT III FREQUENCY RESPONSE ANALYSIS 9
Frequency Response - Bode Plot - Nyquist Plots - Nyquist Stability Criterion - Relative Stability - Gain Margin - Phase Margin - Bandwidth Magnitude Plots - Constant Circles -Nichol's Chart.
UNIT IV PHYSIOLOGICAL CONTROL SYSTEMS 9
Introduction to Physiological Control Systems - Modelling of Human Movements -Parameter Estimation - Linearizing.
UNIT V STUDY OF BIOLOGICAL SYSTEMS 9
Human Thermal System - Neuro Muscular System - Respiratory System - Occulomotor System.
L: 45 T: 15 Total: 60
REFERENCES
1. M. Gopal, "Control Systems, Principles and Design", Tata McGraw-Hill, 1997.
1. Benjamin C. Kuo, "Automatic Control Systems", Prentice Hall of India, 1995.
2. Manfreclyner and John H. Milsum, "Bio Medical Engineering System", McGraw-Hill and Co., New York, 1970.
BIOMATERIALS AND ARTIFICIAL ORGANS
L T P 3 0 0
UNIT I STRUCTURE OF BIOMATERIALS AND BIO-COMPATIBILITY
9
Definition and Classification of Biomaterials - Mechanical Properties - Visco Elasticity -Wound-Healing Process - Body Response to Implants - Blood Compatibility.
UNIT II IMPLANT MATERIALS 9
Metallic Implant Materials - Stainless Steels - Co-Based Alloys - Ti-Based Alloys - Ceramic Implant Materials - Aluminum Oxides - Hydroxyapatite Glass Ceramics Carbons - Medical Applications..
UNIT III POLYMERIC IMPLANT MATERIALS 9
Polymerisation - Polyolefin - Polyamicles - Acryrilic - Polymers - Rubbers - High Strength Thermoplastics - Medical Applications.
UNIT IV TISSUE REPLACEMENT IMPLANTS 9
Soft-tissue Replacements - Sutures - Surgical Tapes - Adhesive - Percutaneous and Skin Implants - Maxillofacial Augmentation - Blood Interfacing Implants - Hard Tissue Replacement Implants - Internal Fracture Fixation Devices - Joint Replacements.
UNIT V ARTIFICIAL ORGANS 9
Artificial Heart - Prosthetic Cardiac Valves - Limb Prosthesis - Externally Powered Limb Prosthesis - Dental Implants.
Total : 45
TEXT BOOK
1. PARK J. B., "Biomaterials Science and Engineering", Plenum Press, 1984.
ENVIRONMENTAL SCIENCE AND ENGINEERING
L
T
P
3 0 0
UNIT I
IMPORTANCE OF ENVIRONMENTAL STUDIES 9
Definition - Scope and Importance - Need for Public Awareness - Forest Resources -Water Resources - Mineral Resources - Land Resources - Energy Resources - Food Resources - Equitable use of Resources for Sustainable Lifestyles.
Concept of Ecosystem - Structure and Function of an Ecosystem - Energy Flow in the Ecosystem - Food Chains - Food Webs - Ecological Pyramids - Definition of Bio-Diversity - Bio-Geographical Classification in India - Value of Bio-Diversity - Bio-Diversity at Global - National and Local Levels - India as a Mega Diversity Nation - Hot Spots of Bio Diversity - Threats to Bio Diversity - Conservation of Bio-Diversity.
UNIT III ENVIRONMENTAL POLLUTION 9
Definition - Causes and Effects of Environmental Pollution - Air Pollution - Water Pollution - Soil Pollution - Marine Pollution - Noise Pollution - Thermal Pollution -Nuclear Hazards - Solid waste management - Societal role in Pollution prevention -Environmental Disasters and management.
UNIT IV SOCIAL ISSUES AND THE ENVIRONMENT 9
Unsustainable to Sustainable Development - Concept of Conservation - Water and Energy Conservation - Rain Water Harvesting - Climate Change - Global Warming - Acid Rain -Ozone Layer Depletion - Nuclear Accidents and Holocaust - Environmental Protection Act - Issues Involved in Enforcement of Environmental Legislation - Public Awareness.
UNIT V HUMAN POPULATION AND THE ENVIRONMENT 9
Population Growth - Population Explosion - Family Welfare Programme - Environment and Human Health - Human Rights - Value Education - HIV / AIDS - Women and Child Welfare - Role of IT in Environment and Human Health.
TEXT BOOKS
1. Gilbert M. Masters, "Introduction to Environmental Engineering and Science", Pearson Education, 2nd Edition, 2004.
2. Miller T. G. Jr., "Environmental Science Working With the Earth", Thomson Learning. 11th edition, 2006.
3. Trivedi R.K and P.K. Goel, "Introduction to Air Pollution", Techno-Science Publications.
REFERENCES
1. Bharucha Erach, "The Biodiversity of India", Mapin Publishing, Ahmedabad.
2. Trivedi R. K., "Handbook of Environmental Laws, Rules, Guidelines, Compliances and Standards", Vol. I and II Environ Media.
3. Cunningham W. P. Copper, T.H. Gorhani, "Environmental Encyclopaedia", Jaico
Publ., Mumbai, 2001.
UNIT II
ECOSYSTEMS AND BIO DIVERSITY 9
Total: 45
MICROPROCESSORS AND MICROCONTROLLERS LABORATORY
LTP 0 0 3
LIST OF EXPERIMENTS
1. Programs for 8/16 Bit Arithmetic Operations (Using 8085).
2. Programs for Sorting and Searching (Using 8085, 8086).
3. Programs for String Manipulation Operations (Using 8086).
4. Programs for Digital Clock and Stop Watch (Using 8086).
5. Interfacing ADC and DAC.
6. Parallel Communication between Two Microprocessor Kits using Mode 1 and
Mode 2 of 8255.
7. Interfacing and Programming 8279, 8259, and 8253.
8. Serial Communication between Two Microprocessor Kits using 8251.
9. Interfacing and Programming of Stepper Motor and DC Motor Speed control.
10. Programming using Arithmetic, Logical and Bit Manipulation Instructions of 8051Microcontroller.
11. Programming and Verifying Timer, Interrupts and UART Operations in 8031 Microcontroller.
12. Communication between 8051 Microcontroller kit and PC.
TOTAL: 45
BIOMEDICAL INSTRUMENTATION LABORATORY
LTP 0 0 3
LIST OF EXPERIMENTS
1. Study of Biological Preamplifiers.
2. Recording of ECG Signal and Analysis.
3. Recording of Audiogram.
4. Recording of EMG.
5. Recording of EEG.
6. Recording of Various Physiological Parameters using Patient Monitoring System and Telemetry Units.
7. Measurement of pH, pO2 and Conductivity.
8. Study and Analysis of Functioning and Safety Aspects of Surgical Diathermy.
9. Mini Project .
Total: 45
DIGITAL SIGNAL PROCESSING LABORATORY
LTP 0 0 3
LIST OF EXPERIMENTS
USING TMS320C5X
1. Study of various Addressing Modes of DSP using Simple Programming Examples
2. Sampling of Input Signal and Display
3. Implementation of FIR Filter
4. Calculation of FFT
USING MATLAB
1. Generation of Signals
2. Linear and Circular Convolution of Two Sequences
3. Sampling and Effect of Aliasing
4. Design of FIR Filters
5. Design of IIR Filters
6. Calculation of FFT of a Signal
TOTAL: 45